Pacific Biosciences Acquires Omniome

Pacific Biosciences Acquires Apton Biosystems

August 2, 2023

Biotechnology

Pacific Biosciences (PacBio) has entered into an agreement to acquire Apton Biosystems, a Pleasanton, California-based developer of high-throughput short-read sequencing instrumentation, to accelerate development of a next-generation, high-throughput short-read sequencer. The all-stock deal provides approximately $85 million upfront (≈6.3M shares) plus up to $25 million in additional consideration contingent on achieving $50 million in revenue, valuing the transaction at up to ~$110 million.

Twist Bioscience Acquires iGenomX

June 30, 2021

Biotechnology

Twist Bioscience acquired iGenomX, a developer of high-throughput multiplex NGS library preparation tools, to expand its NGS workflow capabilities and accelerate customer conversion from microarray genotyping to sequencing-based genotyping. The deal consideration was $35 million (combination of cash and Twist stock, plus up to $5 million contingent stock), and Twist expects modest near-term financial impact with incremental revenue from the acquired business in fiscal 2023.

Illumina Acquires SomaLogic from Standard BioTools

January 30, 2026

Biotechnology

Illumina has completed its acquisition of SomaLogic from Standard BioTools for $350 million in cash plus up to $75 million in near-term performance-based payments, adding SomaLogic's proteomics capabilities to Illumina's multiomics strategy. The deal expands Illumina's ability to integrate SomaLogic's SomaScan platform with its NGS ecosystem, DRAGEN software, and Illumina Connected Multiomics to accelerate proteomics at scale while Standard BioTools receives upfront cash, potential earnouts and ongoing royalties.

Bionano Genomics Acquires BioDiscovery

October 12, 2021

Software

Bionano Genomics agreed to acquire BioDiscovery, a provider of NxClinical genomics analysis software, in a deal worth up to $100 million in cash and equity. The acquisition will integrate BioDiscovery's platform-agnostic analysis and reporting tools with Bionano's optical genome mapping technology to accelerate variant analysis and broaden Bionano's market reach; BioDiscovery founder Soheil Shams will join Bionano as Chief Informatics Officer.

Bionano Genomics Acquires Purigen Biosystems

November 28, 2022

Biotechnology

Bionano Genomics agreed to acquire Purigen Biosystems to integrate Purigen's isotachophoresis (ITP) Ionic Purification System into Bionano's optical genome mapping (OGM) workflow, aiming to simplify ultra-high molecular weight (UHMW) DNA isolation and address difficult sample types. The deal consideration is up to $64 million (including $32 million cash at closing and milestone-contingent payments) and was expected to close by December 8, 2022.

Tome Biosciences Acquires Replace Therapeutics

January 5, 2024

Biotechnology

Tome Biosciences has acquired Replace Therapeutics in a merger valued at $65 million in up-front and near-term milestones and up to $185 million total through a mix of cash and stock. Replace will become a wholly owned subsidiary of Tome, adding its ligase-mediated programmable genomic integration (L-PGI) technology to complement Tome's large-DNA integrase-mediated PGI platform to expand the company's gene‑editing capabilities.