Aceragen Acquires Arrevus to Expand Late-Stage Rare Disease Pipeline

Idera Pharmaceuticals Acquires Aceragen

September 28, 2022

Biotechnology

Idera Pharmaceuticals completed an all-stock acquisition of Aceragen, a privately held biotech focused on rare pulmonary and rheumatic diseases, adding Aceragen's lead programs ACG-701 and ACG-801 to Idera's pipeline. The transaction was structured as a stock-for-stock exchange, includes management appointments from Aceragen, and is expected to provide pro forma cash runway into Q3 2023 while advancing Aceragen's clinical milestones.

Zevra Therapeutics Acquires Acer Therapeutics

November 20, 2023

Pharmaceuticals

Zevra Therapeutics completed the acquisition of Acer Therapeutics in a stock-and-contingent-value-rights transaction, bringing the FDA-approved product OLPRUVA and clinical-stage candidate EDSIVO into Zevra's portfolio and transitioning Zevra to a commercial-stage rare disease company. The deal included Zevra's purchase of Acer's senior secured debt and issuance of approximately 2.96 million shares plus CVRs (up to $76 million), and was followed by a registered direct offering to a healthcare-focused investment fund.

Novartis Acquires Regulus Therapeutics

June 25, 2025

Biotechnology

Novartis has completed the acquisition of Regulus Therapeutics, making Regulus an indirect wholly owned subsidiary following a tender offer and merger. The deal secures Regulus' investigational oligonucleotide therapy farabursen for ADPKD and strengthens Novartis' renal disease pipeline.

Buscar Company Acquires 70% Stake in Armorgenix

June 3, 2025

Pharmaceuticals

Buscar Company (OTC: CGLD) has acquired a 70% equity stake in Armorgenix Company via a strategic stock swap, making Armorgenix a key subsidiary. The deal expands Buscar's portfolio into pharmaceuticals—particularly antiviral and detoxification products such as DetoxShield—and includes plans for a Texas manufacturing facility and a Wyoming entity to manage IP and U.S. commercialization.

Charles River Laboratories Acquires Retrogenix

March 31, 2021

Biotechnology

Charles River Laboratories has acquired Retrogenix Limited, a UK-based contract research organization specializing in cell microarray technology for target receptor identification and off-target profiling. The transaction was for approximately £35 million in cash with up to an additional £5 million contingent on performance, and Retrogenix becomes part of Charles River's Discovery and Safety Assessment segment to expand large-molecule and cell therapy discovery capabilities.

Biogen Acquires Reata Pharmaceuticals

July 28, 2023

Biotechnology

Biogen Inc. agreed to acquire Reata Pharmaceuticals, Inc. for $172.50 per share in cash, representing an enterprise value of approximately $7.3 billion. The acquisition adds Reata's FDA-approved SKYCLARYS (omaveloxolone) for Friedreich's ataxia to Biogen's rare disease portfolio and is expected to be significantly accretive to Biogen's Non-GAAP diluted EPS beginning in 2025; the transaction was anticipated to close in Q4 2023.