Avanos Medical Acquires OrthogenRx for $160M

Avanos Medical Acquires Nexus Medical

September 15, 2025

Medical Devices

Avanos Medical has acquired Nexus Medical, a privately held maker of the TKO anti-reflux needleless connector based in Lenexa, Kansas. The purchase adds Nexus' IV therapy connector technology to Avanos' Specialty Nutrition Systems business to strengthen medication and nutrition delivery in high-acuity settings such as NICUs and PICUs.

Avanos Medical Acquires Diros Technology Inc.

June 19, 2023

Medical Devices

Avanos Medical, a medical device company headquartered in Alpharetta, Georgia, has entered into a definitive agreement to acquire Diros Technology Inc., a Toronto-based maker of radiofrequency (RF) products for chronic pain management. The purchase expands Avanos' RF product portfolio—adding Diros' Trident technology—to complement its COOLIEF cooled radiofrequency offering and strengthen its position in non-opioid, minimally invasive pain treatments.

Envista Acquires Osteogenics Biomedical Business

May 17, 2022

Medical Devices

Envista Holdings Corporation entered into a definitive agreement to acquire Osteogenics Biomedical, Allotech LLC and OBI Biologics (collectively “Osteogenics”), a developer of regenerative dental bone grafting products sold primarily under the Cytoplast brand. The deal, subject to customary regulatory approvals and expected to close in the third quarter, expands Envista’s capabilities in regenerative solutions for periodontists, oral and maxillofacial surgeons and implant dentistry; the transaction is not subject to a financing condition or shareholder vote.

Novartis Acquires Anthos Therapeutics for Up to $3.1 Billion

February 11, 2025

Biotechnology

Novartis has completed the acquisition of Anthos Therapeutics, a Blackstone Life Sciences–backed clinical-stage biopharmaceutical company, in a deal valued at up to $3.1 billion, including $925 million paid upfront. The acquisition gives Novartis ownership of abelacimab, a Phase 3 factor XI inhibitor being developed to prevent stroke and cancer-associated thrombosis, with remaining milestone payments contingent on regulatory and commercial outcomes.

Aspen Medical Products Acquires Advanced Orthopaedics

January 29, 2025

Medical Devices

Aspen Medical Products, the Irvine-based spinal orthopedics manufacturer, has acquired Advanced Orthopaedics, a manufacturer and supplier of bracing solutions and orthopedic soft goods. The acquisition expands Aspen’s product portfolio into the bracing and supports market and is intended to strengthen service to distributors, hospitals, DME suppliers and retail partners while enhancing Aspen’s global reach.

Novartis Acquires Vedere Bio

September 30, 2020

Biotechnology

Novartis has acquired Vedere Bio, a Cambridge-based optogenetics AAV gene therapy company, for $150 million upfront plus up to $130 million in potential regulatory and clinical milestones (total consideration of $280 million). The deal includes Vedere Bio's lead preclinical intravitreal AAV programs focused on pan-genotypic vision restoration; earlier-stage assets were spun out into a newly formed independent company, Vedere Bio II.