Profluent and Eli Lilly Partner on AI-Designed Gene Editing Platform Deal (Up to $2.25B+ in Milestones)

April 28, 2026

Air Street Capital portfolio company Profluent announced a multi-program strategic partnership with Eli Lilly to develop AI-designed recombinases for genetic medicine. Profluent will receive an upfront payment, committed R&D funding, and is eligible for up to $2.25 billion in development and commercial milestones, plus tiered royalties on net sales.

Buyers
Eli Lilly
Targets
Profluent
Industry
Biotechnology
Transaction Type
Growth capital

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