Smith+Nephew Acquires CartiHeal for up to $330 Million

Johnson & Johnson Options to Acquire Sail Biomedicines for $2.58 Billion

August 2, 2026

Biotechnology

Johnson & Johnson entered into strategic agreements with Sail Biomedicines to collaborate on in vivo CAR-T therapies and secured an exclusive option to acquire Sail for $2.58 billion. The deal includes initial payments totaling $785 million (including a $465 million equity investment) and up to $140 million in additional development milestone payments, with the $2.58 billion payable if the option is exercised.

Smith+Nephew Acquires Integrity Orthopaedics

January 21, 2025

Medical Devices

Smith+Nephew completed its acquisition of Integrity Orthopaedics, a US sports medicine company focused on rotator cuff repair. The deal is valued at up to $450 million, with an initial $225 million cash payment and up to an additional $225 million in performance-based payments over five years.

Smith & Nephew Acquires Engage Surgical

January 19, 2022

Medical Devices

Smith & Nephew plc has acquired Orlando-based Engage Surgical, a maker of cementless unicompartmental (partial) knee systems, in a transaction worth up to $135 million (contingent payments). The deal, financed from existing cash and debt facilities, secures unique cementless partial-knee technology for Smith & Nephew to support its Robotics and Real Intelligence strategy and growth in the partial-knee market.

Bioventus Acquires CartiHeal for $500M

August 30, 2021

Medical Devices

Nasdaq-traded Bioventus has elected to exercise its option to acquire Israel-based medical device company CartiHeal following FDA approval of the Agili-C implant, in a deal valued at approximately $500 million. Bioventus plans to work with the CartiHeal team on commercialization and reimbursement activities to bring Agili-C to market.

Medtronic to Acquire Intersect ENT for $1.1 Billion

August 7, 2021

Medical Devices

Medtronic plc entered into a definitive agreement to buy all outstanding shares of Intersect ENT in an all-cash transaction valued at approximately $1.1 billion (at $28.25 per share). The acquisition aims to expand Medtronic’s ENT product portfolio by combining Intersect ENT’s PROPEL and SINUVA sinus implants with Medtronic’s navigation and related tissue health offerings.

Cirtec Medical Acquires Cardea Catheter Innovations

July 26, 2021

Medical Devices

Cirtec Medical has acquired Cardea Catheter Innovations, a San Jose-based manufacturer of minimally invasive catheter devices and complex delivery systems. Cardea will integrate into Cirtec's NovelCath brand to expand the company's interventional capabilities across structural heart, electrophysiology, and neurovascular markets and will relocate into Cirtec's new San Jose Center of Excellence.